Rarest human disorders and Medical Condition in the world
We all have heard of several diseases, seen some of them and even had them personally. However most of us are quite unlikely to get any Rarest human disorders or rare medical disorder and wish for the same for everyone else.
This Rarest human disorders are also known as orphan disease and it’s very uncommon for any doctors to run over it in their practice.
Some of them are hereditary problems, meaning a disease passed on to us from parents by genetically mutation. And other diseases are result of microscopic organisms which are evolved to thrive inside our body. You can read below information to about Rarest human disorders.
Here we enlist few such less known medical conditions to make you aware of:-
Fibrodysplasia ossificans progressiva – “Stone Man Syndrome”
Fibrodysplasia ossificans progressiva (FOP) is a progressive genetic disorder responsible for mutating soft tissues of our body into hard bone over time.
The ACVR1 gene found in bone, muscles, tendons, and ligaments takes care of growth and development of those tissues, and is normally responsible for turning cartilage into bone during the development phase of children. However, mutations of this gene can allow ossification to go unchecked throughout a patient’s life, even turning skeletal muscle into bone and causing joints to fuse together. Aforesaid disease affects in about 1 in 2 million people, and as of now no cure has been found for it. It is also one the Weirdest Diseases in world.
Any kind of trauma can induce the rate of the condition, thus removing bone by means of operations merely results in the body producing even more bone in the area.
Cotard’s Delusion – “Walking Corpse Syndrome”
Cotard’s Delusion is a rare mental disorder in which a person thinks that he is missing some body part—like as the brain—or is actually dead. It is one of the Rarest disorders in world.
Patients usually don’t prefer to eat or bathe, and they often spend time in cemeteries, wishing to be among their own kind. This disorder has been connected to a dysfunction in the areas of the brain responsible for recognizing and associating emotions with faces, even own. This causes a complete emotional detachment and removes any sense of personal identity when looking at their bodies. Medications can be used to treat the condition, though electroconvulsive therapy has worked better in some cases.
Cold Allergy is comes in Rarest human disorders. With winter just around the corner for those living in the Northern Hemisphere, who suffer from cold urticaria need to be prepared. Contact to cold air or water can trigger a histamine reaction, and can cause itchy hives and swelling in the affected areas. It is also one of the Rarest human disorders in world. Those who have severe conditions can experience extreme swelling of the throat and tongue, and be actually fatal. There is no defined reason to causes this condition; however it can be treated with common antihistamines used for those who suffer from pet or seasonal allergies.
Epidermodysplasia Verruciformis, Lewandowsky – Lutz dysplasia, “Tree Man Syndrome”
In this condition something like bark of a tree can be seen growing out of suffers skin. These growths are actually warts that can be induced by exposure to sunlight. While these warts may be benign early in life, they can become malignant later in life. It is also come in Rarest human disorders in world.
The warts are caused by a rare mutation of the EVER1/EVER2 genes. Though the function of the genes isn’t really well-understood, the mutations cause the skin to be extremely susceptible to humanpapillomaviruses 5 and 8, which typically don’t cause disease. While there are some treatment options available to mitigate the symptoms, there is no cure.
Xeroderma Pigmentosum, “Vampire Syndrome”
Humans need sunlight to synthesize vitamin D, but too much exposure to the Sun’s UV rays can damage the skin. Approximately 1 in 1 million people have xeroderma pigments um and are extremely sensitive to UV rays. The patients should avoid any contact with sunlight, or will experience extreme sunburns and breakdown of the skin. If someone with the condition isn’t careful, they could easily develop skin cancer. Xeroderma pigmentosum is caused by a rare recessive mutation of the nucleotide excision repair enzymes. Functioning normally, these enzymes correct damaged DNA that can be caused by UV rays. This is Rarest human disorders in world. For those with this condition, the enzymes do not work properly and DNA damage persists and accumulates. While there are some treatments available, the best prevention from damage is merely staying completely out of sunlight, just like a vampire.
Hypertrichosis – “Werewolf syndrome”
Few hairs between the eyebrows can surely be plucked but for people who suffer from aforesaid syndrome have an abnormal hair growth all over their body. It is one of the Rarest human disorders.
Faces can be completely covered in long hair, which is why the condition has earned the nickname of “werewolf syndrome”. Hypertrichosis can be either congenital or acquired. Those born with the condition can suffer from one of several known genetic mutations. Some who get the condition later in life acquired it as a side effect from anti-balding treatments (be careful what you wish for…), though there are some who do not have an obvious cause. Treatment options include traditional methods of hair removal, though even waxing and laser treatments typically don’t provide long-lasting results.
Aquagenic urticaria – “water allergy”
It’s weird to get an allergy from water as most of the constituent of body is water. However it’s not actually a real allergy as no histamine response is triggered; there are some who develop itchy hives and welts even after mere minutes of water exposure. This condition is quite rare, and the cause isn’t well known. Some believe that the water itself isn’t the cause, but actually specific chemicals or impurities that are mixed within water. However, even purified water can trigger a reaction among some. The most common treatment is topical application of capsaicin, which is used to relieve pain. It is also one the Rare human disorders in world.
You can also watch below video of Top 10 Rare Medical Condition and Diseases in world.
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